Nine Square Therapeutics is discovering new small-molecule therapeutics for degenerative movement disorders including Parkinson's disease and amyotrophic lateral sclerosis (ALS), as well as non-degenerative disorders such as essential tremor and dyskinesias, by integrating computational chemistry, biophysics and computational biology into machine-learning-enabled cell profiling platforms for target identification, chemical optimization and patient stratification.In July 2020, Nine Square Therapeutics formed from a collaboration between Apple Tree Partners (ATP) and scientists at the University of California San Francisco (UCSF)